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Endobronchial ultrasound (EBUS) Procedure

Endobronchial Ultrasound - EBUS Test in Hyderabad, India | Procedure & Cost

PACE Hospitals is one of the best hospital for EBUS test in Hyderabad, offers state-of-the-art facilities, a team of highly skilled pulmonologists, and advanced diagnostic techniques. With a focus on patient comfort and accurate results, the hospital utilizes Endobronchial Ultrasound to visualize and biopsy lung lesions, enabling early detection and diagnosis of lung conditions such as lung cancers and other pulmonary diseases, ensuring the best possible exceptional care for respiratory health.

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    PACE Hospitals is recognized as one of the best hospitals for Endobronchial Ultrasound (EBUS) test in Hyderabad, India. The hospital's pulmonology department is staffed with highly skilled and experienced pulmonologists who specialize in the diagnosis and management of respiratory conditions, various lung conditions, including lung cancer, infections, inflammations, malignancies and other pulmonary diseases.


    PACE Hospitals offer state-of-the-art facilities and advanced medical technology for EBUS testing, ensuring accurate diagnosis and effective treatment of respiratory conditions. The hospital's experienced pulmonologists use the latest EBUS equipment combines bronchoscopy with ultrasound technology to visualize the lungs and surrounding lymph nodes in real-time using high-frequency sound waves and perform the procedure with precision and minimal invasiveness, reducing the risk of complications and improving patient outcomes.


    PACE Hospitals prioritize patient-centered care, ensuring that each patient receives personalized attention and support throughout their treatment journey. The hospital's multidisciplinary team of healthcare professionals works together to develop individualized treatment plans that take into account each patient's unique medical history, diagnosis, and personal preferences. The safety profile of EBUS is favorable, with risks such as bleeding or infection being manageable, making it a preferred choice for lung disease assessment.


    PACE Hospitals' commitment to excellence in EBUS testing, patient-centered care, and cutting-edge medical research make them one of the best Endobronchial Ultrasound testing hospital in Hyderabad. Patients can feel confident in the hospital's ability to provide them with the highest level of care and support throughout their treatment journey.

    Endobronchial ultrasound (EBUS) definition

    The endobronchial ultrasound (EBUS) is a minimally invasive procedure that gives the pulmonologist a picture of the lungs' airways, which helps in the diagnosis of various illnesses affecting the lungs and airways (the tubes that carry air to the lungs) such as infections, lung cancer, and other conditions resulting in enlarged lymph nodes in the chest. The endobronchial ultrasound (EBUS) procedure is performed by a pulmonologist who has undergone adequate training.


    A tiny, flexible, ultrasound-equipped camera is carefully inserted into the lungs through the mouth. The pulmonologist will examine the nearby glands (lymph nodes) using an ultrasound scanner and may use a needle to collect samples.

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    Within the tracheobronchial tree, two types of endobronchial ultrasound are used. Below are the two types of endobronchial ultrasound (EBUS): 

    • Radial probe endobronchial ultrasound (RP-EBUS) 
    • Convex-probe endobronchial ultrasound (CP-EBUS)


    Radial probe endobronchial ultrasound (RP-EBUS): RP-EBUS has been carried out using a radial probe advanced through a bronchoscope's work channel, either with or without a balloon. After processing, the ultrasound waves are transformed into a 360-degree grayscale image. The most common use of RP-EBUS is the assessment of pulmonary nodules. However, even though real-time imaging is available, real-time guidance is not possible.


    Convex-probe endobronchial ultrasound (CP-EBUS): Convex-probe EBUS additionally uses ultrasound technology to examine structures outside of white light bronchoscopy's vision field. The flexible bronchoscope is equipped with a convex ultrasonic transducer at its tip, which creates a greyscale image parallel to the bronchoscope's insertion. To improve surface contact and enhance image quality, a balloon tip filled with saline can be used. Vascular structures can also be distinguished using Doppler imaging.

    EBUS indications

    Although the endobronchial ultrasound (EBUS) test was initially developed for diagnosing and staging non-small cell lung cancer (NSCLC), it is now being used more frequently in nononcologic pulmonary disease conditions. Some of the indications of EBUS include the following:

    • Diagnosis, staging, and restaging of lung cancer: The new guidelines from the American College of Chest Physicians regarding lung cancer diagnosis, staging, and therapy suggest EBUS as the first step in the diagnostic process. Additionally, the European Society of Thoracic Surgeons advises EBUS as the initial option for mediastinal staging in Non-Small Cell Lung Cancer (NSCLC) patients.
    • Mediastinal lymphadenopathy: The area between both lungs is the mediastinum, and inflammation of lymph nodes in the mediastinum is mediastinal lymphadenopathy. For most patients, endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA) is the recommended initial technique for sampling the accessible mediastinal lymph nodes.
    • Endobronchial lesions: Endobronchial ultrasound (EBUS) can more precisely determine if endobronchial lesions are malignant. EBUS helps determine the best treatment and provides a more accurate assessment of mucosal lesions.
    • Lymphoma: If a lymphoma is suspected, EBUS can be used to perform a histologic diagnosis. Later, fluorescence in situ hybridization can be used to further describe the various lymphoma subtypes in the samples that EBUS obtained.

    EBUS contraindications

    Similar to bronchoscopy in general, endobronchial ultrasound has specific contraindications. Below are some of the conditions in which endobronchial ultrasound (EBUS) is not recommended:

    • Current or recent myocardial ischemia: A myocardial infarction, also termed a "heart attack," is caused when blood supply to a part of the myocardium (the thick middle layer of the heart) decreases or is restricted.
    • Life-threatening cardiac arrhythmias: Any problem with the rate or rhythm of the heartbeat is known as an arrhythmia or irregular heartbeat. There are three possible heart rate variations: too fast, too slow, or irregular.
    • Severe hypoxemia: A lower partial pressure of oxygen in arterial blood is known as hypoxemia. This common clinical phenomenon needs to be immediately diagnosed to guide treatment because it can cause tissue hypoxia.
    • Poorly controlled heart failure: When the heart can't pump blood as efficiently as it should, it can develop heart failure. This may happen when the heart muscle weakens or stiffens. As a result, it fails to supply enough blood to the rest of the body, and the body cannot get adequate oxygen or nutrients in such cases.
    • Chronic obstructive pulmonary disease (COPD): It is a condition that restricts airflow and makes breathing difficult. It occurs due to damage to the airways or other parts of the lungs.
    • Coagulopathy or bleeding diathesis: Values vary depending on the operator and the clinical setting, none are universally recommended, yet a platelet count of more than 50,000/ml or an international normalized ratio (INR) of less than 1.5 is usually recommended. 
    • Patient factors: It is essential to consider patient factors like the inability to provide informed consent, drug sensitivity to the use of anaesthesia, and dental or spinal problems that would prevent the patient from passing the scope safely.

    EBUS advantages

    In addition to being more accurate and less invasive, endobronchial ultrasound (EBUS) can be repeated without any limitations that prevent mediastinal restaging by mediastinoscopy. Below are some of the advantages of the EBUS procedure:

    • It provides imaging of the airways, blood vessels, lungs, and lymph nodes in real-time.
    • The enhanced images enable the pulmonologist to view difficult-to-reach areas with greater clarity for access to even smaller lymph nodes for biopsy with the aspiration needle than with conventional mediastinoscopy.
    • The accuracy and rapidity of the EBUS technique facilitate rapid onsite pathologic evaluation. Pathologists in the operating room can examine and process biopsies as they are obtained and can request additional biopsies if necessary.
    • Under moderate sedation or general anesthesia, EBUS is performed.
    • Patients recover rapidly and typically can return home the same day.

    EBUS procedure steps

    The pulmonologist follows the below steps for performing the endobronchial ultrasound (EBUS) procedure:

    Before EBUS procedure

    • Before performing an endobronchial ultrasound (EBUS), the pulmonologist will assess the patient's overall health and take their vital signs, including blood pressure, temperature, and pulse.
    • The EBUS procedure may require 30 to 60 minutes. Nonetheless, patients might need up to four hours for their entire appointment.
    • Before the procedure, patients should fast for at least six hours without eating anything. For up to two hours before, they can only have water—no tea, coffee, or other beverages. For the last two hours, patients need to stay away from all food and liquids.
    • Patients can take regular medications with sips of water, except for blood thinners and diabetic medications. 
    • Patients are advised not to take their diabetes medications on the day of the procedure. If the patient is on insulin, the doctor may inform you before the procedure.
    • It is essential to inform the pulmonologist about all medications, vitamins, and supplements patients use, including over the counter (OTC) medications.
    • Before the procedure, patients must stop using blood thinners; the exact time duration changes depending on the blood thinner type. Ensure they know how long patients must quit before the procedure (in days). After the procedure, patients will be given instructions on when to restart them.
    • Patients should speak with the doctor immediately if they begin taking any new drugs before the procedure to see whether they can continue taking them up to and including the day of the procedure.
    • The patients will have to do a signature on a consent form authorizing the doctors to perform the surgery. Patients should carefully read the form; if there are any questions, they can ask the pulmonologists.
    • An intravenous (IV) line will be inserted into an arm vein before the procedure.
    • Electrocardiogram leads will be attached to the chest to monitor the patient's heart.
    • An intravenous drug will be administered to patients to help them relax and feel sleepy.
    • If necessary, general anesthesia may be given to the patient. The patient and the anesthetist can discuss regarding this.

    During EBUS procedure

    • Patients will lie on their backs while the procedure is being done.
    • Patients will be carefully monitored throughout the procedure, and oxygen may be given to them.
    • Patients who choose to have sedation will receive it before the procedure starts.
    • The bronchoscope, which is a flexible tube with a camera attached, is cautiously inserted through the mouth into the breathing tubes in the lungs.
    • The pulmonologist will numb the windpipe and vocal cords during the procedure with a more local anesthetic spray. Although this will not completely stop the patients from coughing, it will make the procedure more comfortable for them.
    • The pulmonologist will examine the lining of the airways and detect lymph nodes in the lungs that are next to the airways using ultrasound.
    • The bronchoscope will be equipped with an ultrasound probe, which will take pictures. These images will serve as a guide for collecting tissue samples.
    • Tissue samples are obtained using a needle inserted through the bronchoscope.
    • A chest x-ray could be performed.
    • Patients will not be allowed to consume food or liquids until the medication used to numb their throat wears off and their swallowing reflex returns to normal.

    After EBUS procedure

    • The patient may have persistent coughing after the procedure due to lung discomfort. This will gradually go. 
    • Patients may spit out blood-tinged if samples or biopsies are collected.
    • Patients will be monitored for blood pressure, pulse, and oxygen levels in the recovery area, they will not be allowed to drink or eat anything for two hours after the treatment. 
    • After the procedure, patients are advised not to use any machinery or drive a car for 24 hours.
    • Patients may experience sore throats for one to two days. Ice chips or throat lozenges could help reduce the soreness.

    EBUS complications

    An endobronchial ultrasound (EBUS) is a very safe procedure. There is extremely little likelihood that anything will go badly. When problems do arise, they are usually minor and easy to resolve. Below are some of the complications that are associated with EBUS bronchoscopy:

    • Coughing: The patient may have persistent coughing after the procedure due to lung discomfort. This usually goes away as the local anesthetic has action.
    • Bleeding: It occurs from the area where EBUS biopsy samples were collected.
    • Temporary breathlessness: Occasionally, patients may experience temporary breathing difficulties because of irritation of the voice box.
    • Anesthesia undesired effects: Some individuals experience side effects from the sedatives and local anesthetics. There is almost little risk, and treatment can generally reverse it.
    • Breathing difficulty: Rarely, the flexible camera can cause an airway spasm that makes breathing difficult.
    • Pneumothorax (collapsed lung): Collection of air outside the lung but within the pleural cavity. This occurs in less than five percent of patients.
    • Chest infection: The chance of getting a chest infection is minimal; less than 5 out of 100 persons get one. Nevertheless, it will react quickly to antibiotics.
    • Cardiac risk: Patients with underlying cardiac disease may experience an irregular or fast heartbeat.

    EBUS procedure recovery

    Open surgery is riskier and takes more days to recover. Endobronchial ultrasound (EBUS) is often performed as an outpatient procedure and does not involve any incisions. After the EBUS procedure, patients may be able to return to their regular activities the next day, or earlier if they choose not to have anesthesia.

    Questions that the patients can ask the healthcare team about the Endobronchial ultrasound (EBUS) procedure?

    • When will I be able to go home?
    • Will I experience any difficulties after going home?
    • What kind of pain should I expect?
    • When can I return to work?
    • When will I receive the results of my endobronchial ultrasound (EBUS) procedure?
    • What foods and drinks can I consume after the endobronchial ultrasound (EBUS) procedure?
    • Are there any potential long-term effects of this procedure?
    • How long will it take for my cough to go?
    • When am I permitted to drive again?
    • Is further treatment necessary?
    • When should I schedule my next appointment with the doctor?

    Difference between EBUS vs Bronchoscopy

    EBUS vs Bronchoscopy

    A bronchoscopy is a procedure that allows you to see directly into your large airways, which are the bronchi (airway branches) and trachea (windpipe). If a biopsy of the lymph glands in the chest is needed, an EBUS, a kind of bronchoscopy, may be the most suitable procedure. Below are some of the parameters that help in differentiating bronchoscopy and EBUS: 

    Parameters EBUS Bronchoscopy
    Purpose The endobronchial ultrasound (EBUS) is a minimally invasive procedure that gives the pulmonologist a picture of the lungs' airways, which helps in the diagnosis of various illnesses affecting the lungs and airways (the tubes that carry air to the lungs) such as infections, lung cancer, and other conditions resulting in enlarged lymph nodes in the chest. A bronchoscopy is a technique used to see inside the airways and identify lung conditions. Additionally, it can be used when treating specific lung conditions.
    Technique A tiny, flexible, ultrasound-equipped camera is carefully inserted into the lungs through the mouth. A flexible bronchoscope with a camera, light source, and fiber optics offers direct, real-time visualization of the airways.
    Imaging capability Advanced bronchoscopic procedures, like endobronchial ultrasonography, allow for the ultrasonographic examination of mediastinal structures, including lymph nodes and the lung's periphery. The minimally invasive diagnostic bronchoscopy method makes direct visualization and airway samples possible.
    Advantage EBUS test is primarily helpful for getting material from lymph nodes outside the airways, sometimes the only findings of an illness to be identified. EBUS is not helpful for diseases inside the airways where regular bronchoscopy is superior.
    • What is EBUS tbna?

      Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a procedure that helps a pulmonologist view the lungs using an ultrasound probe to collect samples of the glands in the mediastinum or middle part of the chest.

    • How does EBUS work?

      During an EBUS procedure, a thin, flexible tube is used to see inside patients' breathing tubes or airways in the lungs. An ultrasonic probe is attached to the tube. Images produced by high-frequency sound waves show the lungs and other structures outside the airway walls, like the lymph nodes.

    • How long is an EBUS procedure?

      An endobronchial ultrasound (EBUS) procedure usually takes 45 minutes or less, depending on the results and whether therapy is needed. Patients need to prepare to stay in the hospital for two to four hours.

    • Is the EBUS procedure safe?

      Yes, EBUS is a well-established, safe, and minimally invasive procedure for diagnosing and staging lung cancer and other conditions related to mediastinal lymphadenopathy.

    • What is EBUS for lymph nodes?

      For diagnosing and staging hilar and mediastinal lymph nodes, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe procedure that is less invasive than mediastinoscopy and has great accuracy for lung cancer diagnosis.

    Frequently asked questions (FAQs) on EBUS procedure


    What is EBUS?

    The endobronchial ultrasound (EBUS) is a minimally invasive procedure performed by a pulmonologist that visualizes the airway wall and surrounding structures using ultrasound and bronchoscopy. It helps diagnose various illnesses affecting the lungs and airways (the tubes that carry air to the lungs), such as infections, lung cancer, and other conditions resulting in enlarged lymph nodes in the chest.

    Does ROSE increase diagnostic accuracy in EBUS?

    Rapid onsite evaluation (ROSE) of EBUS-TBNA biopsies improves diagnostic accuracy and is a helpful technique for ensuring sample sufficiency. Additionally, it decreases the number of passes obtained for each patient, which may shorten the procedure's duration and lower the patient's risk of complications.

    How long does it take to get EBUS test results?

    To find out the results of EBUS test, patients should make an appointment with the pulmonologist. The results often become available within seven to fourteen days after the test.

    What are the limitations of EBUS test?

    Endobronchial ultrasound (EBUS) cannot stage the complete mediastinum when it comes to mediastinal staging in lung cancer. Endoscopic ultrasound (EUS)is frequently used to sample the posteroinferior mediastinum, while EBUS is limited to the anterosuperior mediastinum.

    What things should be avoided after EBUS?

    Patients are advised not to consume alcohol, operate machinery, drive, sign any legal documents, or go back to work for at least one day after an endobronchial ultrasound (EBUS) procedure. This can be due to the lasting effects of the sedative.

    What is the difference between convex and radial EBUS?

    With one nurse's help, the operator stands at the patient's head while the patient is lying down. The patient may have the EBUS instrument and associated devices, such as a light source, processor, conventional monitor (all in one column), and ultrasound monitor, positioned to the left or right of the patient.

    What is the positioning for EBUS?

    With one nurse's help, the operator stands at the patient's head while the patient is lying down. The patient may have the EBUS instrument and associated devices, such as a light source, processor, conventional monitor (all in one column), and ultrasound monitor, positioned to the left or right of the patient.

    Does EBUS require anesthesia?

    A variety of sedatives, including general anesthesia and mild sedatives, can be used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).

    What is the cost of EBUS test in Hyderabad, India?

    Endobronchial ultrasound - EBUS test cost in Hyderabad can vary from ₹25,000 to ₹65,000 (US$1600 - US$2500), depending on several factors, including the requirement for additional biopsies and transbronchial needle aspiration (TBNA) during outpatient or inpatient​, type of procedure, hospital facility, and any post-operative care required.


    It is important to note that these costs are approximate and can vary based on individual patient needs and circumstances. Additional expenses, such as hospital stay, anesthesia fees, medications, and follow-up appointments, may also apply. It is also recommended to consult with a pulmonologist to obtain a detailed and personalized cost estimate based on individual 

    When was EBUS first used?

    Herth et al. reported the first use of radial probe endobronchial ultrasound (RP-EBUS) to guide transbronchial biopsies for lung nodule assessment in 2002.


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