Successful Laparoscopic Pancreaticojejunostomy with Splenectomy for Acute-on-Chronic Pancreatitis

PACE Hospitals

PACE Hospitals’ expert Surgical Gastroenterology team successfully performed Laparoscopic Pancreaticojejunostomy with Splenectomy on a 38-year-old male patient diagnosed with acute-on-chronic pancreatitis, a complex pancreatic pseudocyst, pancreatic duct stones and a dilated pancreatic duct. The procedure aimed to improve pancreatic juice drainage, relieve recurrent abdominal pain, manage the pseudocyst and prevent further complications associated with chronic pancreatitis.


Chief Complaints

A 38-year-old male patient with a body mass index (BMI) of 18 presented to the Surgical Gastroenterology Department at PACE Hospitals, Hitech City, Hyderabad, with complaints of recurrent episodes of upper abdominal pain for the past few months.

Past Medical History

The patient had no significant past medical or surgical history. He had no known chronic illness, previous major surgery, or medication allergy.

On Examination

On examination, the patient was conscious, coherent, oriented, and hemodynamically stable. Abdominal examination revealed mild tenderness in the upper abdomen without guarding, rigidity, or signs of acute peritonitis. The remaining systemic examination was normal.

Diagnosis

Upon admission to PACE Hospitals, following a detailed clinical assessment, the Surgical Gastroenterology team evaluated the patient for recurrent upper abdominal pain that had been present for the past few months. His previous CT and contrast-enhanced CT findings were reviewed as part of the evaluation.


Imaging revealed acute-on-chronic pancreatitis with a complex pancreatic pseudocyst involving the head and neck of the pancreas, along with moderate ascites. The diagnosis was established based on the patient’s clinical presentation, imaging findings, and further evaluation performed after admission.


Routine investigations, including complete blood count, serum biochemistry, pancreatic function tests, and other preoperative assessments, were performed to evaluate the patient’s overall medical condition and fitness for surgery. These investigations also assisted the surgical team in planning the appropriate treatment.


Based on the confirmed diagnosis, the patient was advised to undergo Acute-on-Chronic Pancreatitis with Pancreatic Pseudocyst Treatment in Hyderabad, India, under the expert care of the Surgical Gastroenterology Department.

Medical Decision Making (MDM)

After detailed consultation with Dr. Govind Verma, Dr. M Sudhir, Dr. Prashanth Sangu, and Dr. Suresh Kumar S, a comprehensive clinical evaluation was performed to determine the most appropriate treatment approach for the patient presenting with recurrent upper abdominal pain. The patient’s previous CT and contrast-enhanced CT findings were reviewed, and further investigations and pre-anaesthetic assessment were carried out to evaluate his fitness for surgery.


Considering the patient’s clinical presentation and imaging findings, the diagnosis of acute-on-chronic pancreatitis with a complex pancreatic pseudocyst involving the head and neck of the pancreas, moderate ascites, pancreatic duct stones, and pancreatic duct dilatation was confirmed. Routine laboratory investigations and standard preoperative assessments were performed to evaluate his overall medical condition and plan the surgical procedure.


Based on the clinical assessment, imaging findings, and obstructed dilated pancreatic duct, it was determined that laparoscopic pancreaticojejunostomy with splenectomy was the most appropriate management strategy. Pancreaticojejunostomy was planned to improve pancreatic duct drainage, relieve ductal pressure, manage the obstructing stones, and reduce recurrent abdominal pain. Splenectomy was included based on the extent of the associated disease and intraoperative findings.


The patient and his family members were counselled regarding the diagnosis, proposed surgical procedure, expected benefits, potential risks, postoperative drain care, recovery, and the importance of adhering to medications, dietary advice, and scheduled follow-up for optimal outcomes.

Surgical Procedure

Following the clinical decision, the patient was scheduled for Laparoscopic Pancreaticojejunostomy with Splenectomy in Hyderabad at PACE Hospitals under the expert care of the Surgical Gastroenterology Department.


The following steps were carried out during the procedure:


  • Patient Preparation and Laparoscopic Access: After preoperative investigations, anaesthetic clearance, and informed consent, the patient was taken up for surgery under general anaesthesia. The abdomen was prepared under strict aseptic precautions. Laparoscopic ports were placed to access the pancreas, spleen, and surrounding structures.


  • Pancreatic Assessment and Exploration: The pancreas and nearby tissues were carefully examined during surgery. An intrapancreatic pseudocyst involving the head of the pancreas was identified, along with a firm pancreatic texture. The main pancreatic duct was dilated, with multiple stones present inside it.


  • Pancreatic Duct Opening and Stone Removal: The main pancreatic duct was identified and opened longitudinally along the affected portion. Multiple pancreatic duct stones and obstructing material were carefully removed. The duct was cleared adequately to improve the drainage of pancreatic secretions.


  • Pancreaticojejunostomy and Splenectomy: A loop of the jejunum was connected to the opened pancreatic duct to create a side-to-side pancreaticojejunostomy. This allowed pancreatic secretions to drain into the small intestine and reduced pressure within the duct. Splenectomy was also performed based on the associated disease and intraoperative findings.


  • Drain Placement and Closure: After ensuring adequate haemostasis and checking the surgical connection, drains were placed near the pancreas and splenic fossa. A percutaneous catheter drainage tube was maintained to drain the associated ascitic fluid. The laparoscopic ports were removed, and the incisions were closed in layers.

Postoperative Care

The postoperative period was uneventful. The patient was closely monitored for vital signs, abdominal symptoms, drain output, bowel function, and tolerance to oral intake. Intravenous treatment was provided for infection prevention, pain control, gastric protection, hydration, and supportive care. A liquid diet was started from the second postoperative day, and the splenic fossa drain was removed after satisfactory recovery.

Discharge Medications

Upon discharge, the patient was prescribed oral medications to prevent infection, reduce pain and inflammation, protect the stomach, relieve indigestion, and maintain regular bowel movements. Additional supportive treatment was advised as required during recovery.

Advice on Discharge

The patient was advised to take all prescribed medicines, keep the wound and drain clean, and attend follow-up as scheduled. Immediate medical attention was recommended for fever, severe abdominal pain, vomiting or unusual drain output.

Emergency Care

The patient was advised to report to the emergency ward at PACE Hospitals in case of fever, abdominal pain, wound discharge, bleeding, vomiting, severe pain, drain-related concerns, or any other emergency symptoms.

Review and Follow-up Notes

The patient was advised to return for a follow-up visit with the Surgical Gastroenterologist in Hyderabad at PACE Hospitals after five days for wound and drain assessment, recovery evaluation, and further postoperative guidance.

Conclusion

This case highlights the successful use of laparoscopic pancreaticojejunostomy with splenectomy in managing acute on chronic pancreatitis with a complex pseudocyst and pancreatic duct stones. Timely surgical intervention and postoperative care helped the patient recover without complications.

Managing Complex Pancreatic Pseudocysts

Complex pancreatic pseudocysts may develop as a complication of chronic pancreatitis and can be associated with pancreatic duct obstruction, ductal stones, abdominal pain, infection or fluid accumulation. Treatment depends on the size and location of the pseudocyst, the condition of the pancreatic duct and the involvement of nearby organs. A Surgical Gastroenterologist / Surgical Gastroenterology doctor may recommend endoscopic drainage, percutaneous drainage or surgery when symptoms persist or complications develop. Pancreaticojejunostomy may be considered when the pancreatic duct is dilated and obstructed, as it helps improve the drainage of pancreatic secretions. Additional procedures may be required if the spleen, nearby blood vessels or surrounding structures are affected. Careful postoperative monitoring, nutritional support and regular follow-up are important for improving recovery and reducing the risk of recurrence.

Frequently Asked Questions (FAQs)


  • Why is laparoscopic pancreaticojejunostomy recommended for chronic pancreatitis with pancreatic duct stones?

    Laparoscopic pancreaticojejunostomy may be recommended when chronic pancreatitis causes persistent pain along with a dilated or obstructed pancreatic duct. The procedure creates a drainage pathway between the pancreatic duct and the small intestine, helping pancreatic secretions flow more freely. It is generally considered when medicines or suitable endoscopic treatments do not provide adequate relief.

  • Is pancreaticojejunostomy the same as the Puestow procedure?

    A longitudinal pancreaticojejunostomy is commonly referred to as the modified Puestow or Partington–Rochelle procedure. During surgery, the main pancreatic duct is opened along its length and connected to the small intestine. This helps drain the obstructed duct while preserving most of the pancreas.

  • Is a 7 mm pancreatic duct suitable for pancreaticojejunostomy?

    A pancreatic duct measuring around 7 mm may be considered dilated and may allow a drainage procedure in selected patients. However, duct size alone does not determine suitability. A Surgical Gastroenterologist / Surgical Gastroenterology doctor also considers the location of stones, strictures, pseudocysts, pancreatic-head enlargement and the patient’s overall condition.

  • Why may splenectomy be performed along with pancreaticojejunostomy?

    Splenectomy is not routinely required with pancreaticojejunostomy. It may be performed when the pseudocyst or pancreatic inflammation involves the spleen or splenic blood vessels, or when preserving the spleen is considered unsafe during surgery. The exact reason should be confirmed from the operative findings documented by the treating surgeon.

  • Does pancreaticojejunostomy completely remove a pancreatic pseudocyst?

    The procedure mainly relieves obstruction and improves drainage of the pancreatic duct. A pseudocyst that communicates with the duct may reduce after effective drainage, while some pseudocysts may require separate internal, endoscopic or percutaneous drainage. Treatment depends on the pseudocyst’s size, location, complications and connection with the pancreatic duct.

  • Can abdominal pain return after pancreaticojejunostomy?

    Many appropriately selected patients experience meaningful pain relief after pancreatic duct drainage surgery, but complete and permanent relief cannot be guaranteed. Chronic pancreatitis is an irreversible condition, and pain may persist or return because of continued inflammation, nerve changes or further duct obstruction. Avoiding alcohol and smoking and attending regular follow-ups remain important.

  • Will the patient need pancreatic enzyme supplements after surgery?

    Some patients with chronic pancreatitis develop pancreatic exocrine insufficiency and may not produce enough enzymes to digest food properly. Enzyme replacement may be advised when there are oily stools, diarrhoea, bloating, weight loss or poor nutrient absorption. The need and dosage should be assessed by the treating team.

  • Can diabetes develop after pancreaticojejunostomy?

    Chronic pancreatitis can gradually damage the insulin-producing cells of the pancreas, increasing the risk of diabetes. Pancreaticojejunostomy mainly improves duct drainage and does not restore pancreatic tissue that has already been damaged. Blood glucose should therefore be monitored during follow-up, particularly if increased thirst, frequent urination or unexplained weight loss develops.

  • What precautions are required after splenectomy?

    The spleen helps protect the body against certain serious bacterial infections. After splenectomy, patients should follow medical advice regarding pneumococcal, meningococcal and Hib vaccinations, along with other recommended vaccines and boosters. Fever after spleen removal requires prompt medical assessment because infection can sometimes progress rapidly.

  • What follow-up and warning signs are important after this surgery?

    Follow-up is required to assess the wound, drain output, food tolerance, weight, blood glucose and digestive function. The patient should seek immediate medical attention for fever, worsening abdominal pain, repeated vomiting, wound discharge, breathing difficulty, bleeding or a sudden change in drain output. Normal activities should be resumed gradually according to the surgeon’s advice.

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