Usually, the presence of a condition called macrocytic anemia is what makes doctors suspect and begin to look for vitamin B12 Deficiency. But macrocytic anemia is the result of years of vitamin B12 deficiency. This means that until a doctor is willing to even LOOK FOR the easily correctable problem of vitamin B 12 deficiency, a patient will have suffered for years with symptoms. This would have been prevented if they had looked for the deficiency based simply on one of the most common physical complaints that patients have- fatigue.
Fatigue is a problem that affects most of the population at one time or another, but when it becomes chronic it can seriously affect quality of life to the extent that people become disabled. While fatigue can have MANY different causes, one underappreciated cause of fatigue is Vitamin B 12 deficiency.
When doctors suspect vitamin B12 deficiency, they will often do a routine blood test that checks for a condition called macrocytic anemia. Macrocytic anemia is characterized by particularly large red blood cells that are accompanied by a decreased Number of total cells. It is often a Consequence of vitamin B12 deficiency, but can have several other causes as well. Macrocytic anemia, however, is NOT vitamin B12 deficiency, and Vitamin B 12 deficiency can exist with or without the presence of macrocytic anemia. In fact, macrocytic anemia may not occur for up to 2 years after the Start of vitamin B12 deficiency, yet the 'standard of care' that doctors use has them look for vitamin B12 deficiency ONLY if macrocytic anemia is present!
"clinical features that are associated with
vitamin B12 deficiency may indeed precede
evidence of macrocytic anemia"
How B12 Deficiency Can Impact on the Individual...
If Vitamin B 12 deficiency were a rare problem that required expensive and invasive testing in order to find, this would be a reasonable way to look for this problem. But vitamin B12 deficiency is VERY common and testing is as easy as a simple blood test done right in the same lab that tests for macrocytic anemia! In addition, just like other medical problems that are evaluated on their OWN signs and symptoms, vitamin b12 deficiency ALSOhas its OWN signs and symptoms that can be evaluated in the same way.
Vitamin B12 deficiency has a whole list of common presenting features that include:
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