Best Fertility Hospital in Hyderabad, India for IVF, IUI & ICSI
PACE Hospitals is recognized as one of the best hospitals for infertility treatment in Hyderabad, Telangana, India. Our multidisciplinary team of infertility specialists—including reproductive endocrinologists, andrologists, and gynecologists—offers advanced diagnostic evaluations and individualized care for both male and female infertility. From ovulation disorders and tubal blockages in women to sperm abnormalities and hormonal imbalances in men, we address a wide range of reproductive challenges using evidence-based approaches such as ovulation induction, intrauterine insemination (IUI), in vitro fertilization (IVF), and assisted reproductive technologies (ART).
We understand that infertility is not just a medical condition but an emotional journey. At PACE Hospitals, we provide compassionate, patient-focused care in a supportive and confidential environment. Our specialists work closely with each couple to develop personalized treatment plans that align with their medical needs and family-building goals.
Book an appointment for Fertility Treatment
Infertility Treatment Appointment
Why Choose PACE Hospitals for Fertility Treatment?
Advanced Diagnostic Facilities - Comprehensive Semen Analysis, Hormonal Profiling, Scrotal Ultrasound
Best Urologists, Andrologists & Endocrinologists in Hyderabad, India
Minimally Invasive Surgical Options - Varicocelectomy, TESA, PESA, and Vasectomy Reversal
Affordable & Transparent Infertility Treatment with Insurance & Cashless Options
Diagnosis of Infertility
Infertility diagnosis involves a structured and comprehensive evaluation of both partners to identify medical, hormonal, anatomical, or lifestyle-related causes of delayed conception. This process aims to define the underlying reason for infertility and guide appropriate treatment decisions. Diagnosis generally begins after one year of unprotected intercourse, or six months if the woman is over the age of 35.
Female Infertility Diagnosis
Female infertility diagnosis involves a structured sequence of clinical assessments to uncover physiological, hormonal, and anatomical causes that may affect ovulation, fertilization, or implantation. The primary components of diagnostic evaluation in women include:
- Medical History Taking
- Physical Examination
- Lifestyle and Environmental Assessment
- Infectious Disease Screening
- Diagnostic Testing
Medical History Taking: A thorough medical and reproductive history is taken, including menstrual patterns, contraceptive use, past pregnancies, surgeries, infections, and general health. Information on cycle regularity, pain, or abnormal bleeding can help identify ovulatory or uterine issues.
Physical Examination: A general and pelvic examination is performed to check for signs of hormonal imbalance (e.g., hirsutism, acne), thyroid dysfunction, or reproductive tract abnormalities such as uterine enlargement or adnexal masses.
Lifestyle and Environmental Assessment: Risk factors such as obesity, smoking, alcohol use, poor nutrition, or exposure to environmental toxins are evaluated. Addressing modifiable lifestyle elements can enhance treatment success.
Infectious Disease Screening: Screening for sexually transmitted infections like chlamydia and gonorrhea, as well as HIV and hepatitis, is advised especially before assisted reproductive procedures.
Diagnostic Testing: Diagnostic testing involves a targeted series of laboratory and imaging-based evaluations that help pinpoint specific physiological causes of infertility
The specific tests chosen depend on the individual’s clinical background and suspected causes. The key diagnostic categories evaluated in this phase include assessment of ovulation, ovarian reserve, tubal integrity, hormone levels, and uterine structure. The primary components of diagnostic testing in women include:
- Ovulatory Assessment
- Ovarian Reserve Testing
- Tubal Patency Tests
- Hormonal Testing
- Uterine Evaluation
Ovulatory Assessment: Ovulation is generally evaluated using mid-luteal phase serum progesterone testing and by assessing menstrual regularity. Ovulatory dysfunction is a major cause of female infertility and may require further endocrine workup if an ovulation is suspected.
Ovarian Reserve Testing: This assesses the remaining quantity and quality of a woman’s eggs. Common tests include anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), and antral follicle count (AFC) by transvaginal ultrasound. These results help predict response to ovarian stimulation.
Tubal Patency Tests: Hysterosalpingography (HSG) and saline infusion sonography (SIS) are used to assess whether the fallopian tubes are open. Blockages or structural abnormalities identified through these tests may require surgical intervention or assisted reproductive technology (ART).
Hormonal Testing: A full hormonal profile may include FSH, LH, prolactin, TSH, and androgens. These help to detect conditions like PCOS, hyperprolactinemia, thyroid dysfunction, or premature ovarian insufficiency.
Uterine Evaluation: Uterine abnormalities such as polyps, Uterine fibroids, or congenital defects can affect implantation. Evaluation may involve transvaginal ultrasound, hysterosonography, or diagnostic hysteroscopy to detect and sometimes treat intrauterine pathology.
Male Infertility Diagnosis
Male infertility diagnosis follows a structured approach similar to female evaluation, comprising both foundational assessments and targeted diagnostic investigations. The goal is to identify underlying causes affecting sperm production, quality, or delivery by examining physical, hormonal, genetic, and environmental factors. The primary components of diagnostic evaluation in men include:
- Medical History Taking
- Physical Examination
- Lifestyle and Environmental Assessment
- Infectious Disease Screening
- Diagnostic Testing
Medical History Taking: The healthcare expert records childhood illnesses, puberty onset, infections (e.g., mumps orchitis), surgeries, trauma, and any medications or toxins that may affect fertility. Sexual and reproductive history including libido, erectile function, and ejaculation are also explored.
Physical Examination: Examination includes assessment of secondary sexual characteristics, testicular volume, consistency, and the presence of varicoceles or absence of vas deferens. These findings may guide the need for hormonal or genetic testing.
Lifestyle and Environmental Assessment: Lifestyle review includes alcohol and tobacco use, drug exposure, occupational hazards, and heat exposure (e.g. tight clothing). These factors can affect sperm production and quality.
Infectious Disease Screening: Men are routinely screened for infections such as HIV, hepatitis B and C, and sexually transmitted infections (STIs), especially when preparing for ART. These infections may impact reproductive health or require precautions during treatment.
Diagnostic Testing: Male infertility diagnosis evaluates sperm production, structure, motility, and delivery issues. The primary categories of diagnostic evaluation in men include:
- Semen Analysis
- Male Hormonal Testing
- Genetic Testing
- Imaging and Biopsy
Semen Analysis: This is the foundational test for male fertility, evaluating sperm count, motility, morphology, volume, and concentration using WHO criteria. Abnormal values often necessitate repeat testing and further investigation.
Male Hormonal Testing: Hormonal evaluation includes serum FSH, LH, and prolactin levels. These hormones regulate spermatogenesis and are useful in diagnosing disorders such as hypogonadism or hyperprolactinemia.
Genetic Testing: Men with very low or absent sperm counts may undergo karyotyping, Y chromosome microdeletion testing, particularly when congenital bilateral absence of the vas deferens is suspected.
Imaging and Biopsy: Scrotal ultrasound is used to assess varicoceles, testicular structure, or blockages in the reproductive tract. Testicular biopsy is indicated in azoospermic men to distinguish between obstructive and non-obstructive causes.
Couple-Based Evaluation
Infertility often arises from multiple factors and can involve both partners, necessitating simultaneous evaluation. Integrated analysis of male and female findings facilitates accurate diagnosis and efficient treatment planning. Psychological support and counseling may prove beneficial throughout the diagnostic process.
Fertility Treatment
Infertility treatment encompasses a comprehensive set of medical and procedural interventions aimed at addressing the inability to conceive after a prolonged period of unprotected intercourse. These treatments are tailored based on whether the cause lies with the female, male, or both partners. Approaches range from lifestyle modifications and hormonal therapies to advanced reproductive technologies. A stepwise progression is typically followed, starting from the least invasive to the most complex interventions, depending on the underlying diagnosis.
Infertility Treatment in Women
Female infertility treatments address a wide spectrum of reproductive challenges, including hormonal disorders, ovulatory dysfunction, anatomical abnormalities, and uterine receptivity issues. Treatment strategies are typically customized based on diagnostic findings and may range from medication and surgery to advanced reproductive technologies. The choice of treatment is influenced by the woman’s age, reproductive history, underlying condition, and response to previous therapies.
The primary categories of infertility treatments for women include:
- Ovulation Induction Therapy
- Gonadotropin Therapy
- Hormonal Modulation
- Reproductive Surgery
- Assisted Reproductive Technologies (shared with male treatments)
- Advanced and Adjunctive Procedures
- Lifestyle modifications
Ovulation Induction Therapy
Ovulation induction therapy is used to stimulate the development and release of a mature egg in individuals who do not ovulate or have irregular ovulatory cycles. These agents work by influencing the pituitary-ovarian axis to promote follicular growth and hormonal balance.
Ovulation induction is most used in conditions such as polycystic ovary syndrome and unexplained anovulation. It is typically administered in oral or injectable form and is monitored via ultrasound and hormonal assays to ensure appropriate response. This therapy is frequently combined with timed intercourse or intrauterine insemination to maximize conception chances.
Gonadotropin Therapy
Gonadotropin therapy involves the use of exogenous reproductive hormones to induce multifollicular development, particularly in controlled ovarian stimulation cycles. These injectable agents include gonadotropin preparations containing follicle-stimulating hormone and luteinizing hormone.
Gonadotropin therapy is indicated when oral ovulation induction fails or when multiple follicles are required for procedures such as IVF. Because of the heightened risk of ovarian hyperstimulation and multiple pregnancies, this approach requires meticulous cycle monitoring through serial imaging and blood work.
Hormonal Modulation
Hormonal modulation is applied in individuals with underlying endocrine conditions that disrupt reproductive physiology. Common targets include elevated prolactin, insulin resistance, subclinical hypothyroidism, and luteal phase insufficiency.
Medications such as dopamine agonists, insulin sensitizers, and thyroid hormone replacements are tailored to normalize endocrine parameters and create a conducive hormonal environment for ovulation and implantation. While not directly ovulation-inducing, hormone modulators are essential for treating root causes of infertility and are frequently combined with other interventions.
Reproductive Surgery
Reproductive surgery in women addresses anatomical impairments to fertility such as tubal occlusion, endometriosis, fibroids, polyps, or uterine malformations. Laparoscopy is utilized for pelvic pathologies including endometriosis, ovarian cysts, and adhesions, allowing for restoration of normal pelvic anatomy.
Hysteroscopy is indicated for intrauterine corrections such as removal of fibroids, polyps, or adhesions, and for resection of uterine septa. Surgical correction significantly improves the uterine environment and tubal patency, both of which are critical for natural and assisted conception.
Assisted Reproductive Technologies
Assisted Reproductive Technologies (ART) in women involve medical procedures that manipulate eggs, sperm, or embryos to enhance the chances of conception. These techniques are often used when other fertility treatments have failed or are not suitable. ART is especially effective in cases of tubal factor infertility, advanced maternal age, diminished ovarian reserve, or unexplained infertility.
The primary ART techniques specific to female infertility management include:
Intrauterine Insemination (IUI)
Involves placing prepared sperm directly into the uterus around the time of ovulation to facilitate fertilization. Often combined with ovulation induction.
In Vitro Fertilization (IVF)
Involves ovarian stimulation, egg retrieval, laboratory fertilization with sperm, and embryo transfer into the uterus. It is widely used in various female infertility conditions.
Frozen Embryo Transfer (FET)
Embryos created in a previous IVF cycle are frozen and transferred in a later cycle. This allows for better cycle planning and uterine receptivity.
Donor Egg Use
Indicated in cases where the woman cannot produce viable eggs. Donor eggs are fertilized with sperm and the resulting embryos are transferred to the recipient's uterus.
Gestational Surrogacy
Used when a woman cannot carry a pregnancy. An embryo created from the intended parents' or donors' gametes is transferred to the uterus of a surrogate.
Fertility Preservation (Egg Freezing)
Oocytes are harvested and cryopreserved for future use. It is commonly used before cancer treatments or for elective fertility preservation.
These ART techniques are selected based on the woman’s clinical profile, reproductive history, and overall treatment goals.
Advanced and Adjunctive Procedures
Advanced and adjunctive reproductive techniques enhance the success and personalization of infertility treatment. These methods are commonly integrated with standard ART protocols or used to better inform treatment decisions.
- Preimplantation Genetic Testing (PGT): This technique involves screening embryos created through IVF for chromosomal abnormalities or specific genetic conditions before transfer. PGT is particularly helpful for patients with recurrent pregnancy loss, advanced maternal age, or known genetic risks.
- Endometrial Receptivity Analysis (ERA): ERA is a diagnostic test that evaluates the receptivity of the endometrial lining. By identifying the optimal window for embryo implantation, ERA can improve implantation rates in women who have experienced repeated IVF failures.
- Time-Lapse Embryo Monitoring: This technique uses continuous imaging within incubators to monitor embryo development without disturbing the culture environment. It allows embryologists to select the most viable embryos based on dynamic developmental criteria.
- Fertility Preservation (Oocyte and Embryo Freezing): Preserving eggs or embryos for future use is recommended for women facing medical treatments that may impact fertility or those choosing to delay childbearing. This option provides flexibility and control over reproductive planning.
These procedures are chosen based on individual clinical history, prior treatment outcomes, and specific fertility goals.
Lifestyle modifications
Lifestyle optimization plays an important role in managing female infertility, particularly when reproductive outcomes may be influenced by modifiable factors.
Women are encouraged to maintain a healthy body weight, as both underweight and overweight conditions can disrupt ovulatory function. Regular, moderate physical activity helps regulate metabolism and hormonal balance. Cessation of tobacco and alcohol use is important, as both are linked to reduced fertility and adverse pregnancy outcomes.
Nutritional guidance with emphasis on a balanced diet rich in antioxidants and essential micronutrients supports reproductive health. Stress-reduction techniques, including mindfulness and counseling, may also have a beneficial impact on hormonal stability and treatment response.
These lifestyle strategies are not standalone treatments but serve to complement medical and procedural fertility therapies in women.
Infertility Treatment in Men
Infertility treatments for men address various conditions affecting sperm production, function, and delivery. These interventions range from hormonal regulation and surgical correction to advanced sperm retrieval methods and assisted reproductive technologies. Treatment choice is guided by the underlying cause of infertility, the severity of sperm abnormalities, and the couple’s reproductive goals.
The primary categories of infertility treatments for men include:
- Endocrine-Based Treatment
- Surgical Interventions
- Sperm Retrieval Techniques
- Assisted Reproductive Technologies
- Lifestyle and Supportive Measures
Endocrine-Based Treatment
Endocrine-based treatments are used when male infertility is linked to hormonal imbalances affecting sperm production. These treatments may involve the use of gonadotropins to stimulate testicular function or agents that suppress excess estrogen or prolactin levels. Such therapies require hormonal evaluation and ongoing monitoring and are particularly effective in men with hypogonadotropic hypogonadism or other endocrine dysfunctions.
Surgical Interventions
Surgical correction may be indicated in cases of anatomical abnormalities contributing to infertility. The most common surgical procedure is varicocelectomy, which involves repairing dilated scrotal veins associated with impaired sperm production. Other surgeries include correction of ejaculatory duct obstruction or reversal of previous sterilization procedures. The success of surgical intervention depends on the nature and extent of the condition being treated.
Sperm Retrieval Techniques
Sperm retrieval techniques are employed in men with azoospermia—either obstructive or non-obstructive. Methods such as testicular sperm aspiration (TESA), testicular sperm extraction (TESE), and microsurgical epididymal sperm aspiration (MESA) enable the collection of viable sperm directly from the testes or epididymis. These procedures are typically used in conjunction with ICSI as part of an IVF cycle.
Assisted Reproductive Technologies
Assisted Reproductive Technologies (ART) for male infertility aim to address challenges related to sperm production, function, or delivery that hinder natural conception. These procedures are often employed in coordination with female ART strategies but focus specifically on optimizing the male contribution to fertilization.
The primary ART techniques specific to male infertility management include:
- Intracytoplasmic Sperm Injection (ICSI): Used when sperm quality is severely impaired, ICSI involves injecting a single viable sperm directly into an egg. This is particularly useful in cases of low sperm count, poor motility, or use of surgically retrieved sperm.
- Donor Sperm Use: Donor sperm is considered when the male partner cannot produce viable sperm or has genetic issues that contraindicate using his own sperm. It is used in assisted procedures involving the female partner, such as IUI or IVF.
- Surgical Sperm Retrieval (TESA, TESE, MESA): These techniques are used to collect sperm directly from the testes or epididymis when sperm is absent in the ejaculate. The retrieved sperm is typically used in ICSI.
- Fertility Preservation (Sperm Cryopreservation): Sperm freezing allows for long-term storage of viable sperm prior to treatments like chemotherapy that could impair fertility. Preserved sperm can later be used in ART procedures depending on future reproductive plans.
These male-specific ART methods play a critical role in comprehensive fertility care and are selected based on the nature and severity of the male factor involved.
Lifestyle and Supportive Measures
Lifestyle and supportive measures are integral to male fertility management, particularly when sperm quality or function is affected by modifiable risk factors. Maintaining a healthy body weight is important, as both obesity and being underweight can disrupt hormonal balance and impair spermatogenesis. Men are strongly advised to avoid tobacco, excessive alcohol, and recreational drugs, all of which are linked to reduced semen quality and hormonal disruption.
Physical activity should be regular but moderate—intense training or use of anabolic steroids can be detrimental to sperm production. Environmental exposures such as prolonged heat (e.g., hot tubs, saunas), tight clothing, and occupational toxins should be minimized.
A nutrient-dense diet that includes antioxidants, zinc, selenium, and coenzyme Q10 may support sperm motility and morphology. Proper sleep, mental health support, and stress management techniques also contribute to hormonal stability and improved reproductive function.
These measures are not curative on their own but are critical in optimizing outcomes from concurrent medical or assisted reproductive treatments.
Difference Between PCOS and Infertility
PCOS vs Infertility
Polycystic Ovary Syndrome (PCOS) and infertility are two common yet often misunderstood conditions that impact women's reproductive health. While PCOS is a specific hormonal disorder, infertility is a broader term referring to difficulty in conceiving. The table below outlines key differences to help distinguish between these two conditions in terms of causes, symptoms, and diagnosis.
| Aspect | PCOS (Polycystic Ovary Syndrome) | Infertility |
|---|---|---|
| Definition | A hormonal disorder causing enlarged ovaries with cysts. | Inability to conceive after 12 months of trying. |
| Cause | Endocrine imbalance (often high androgens, insulin issues). | Can result from various causes (PCOS, age, male factors, etc.). |
| Primary Symptoms | Irregular periods, excess hair growth, acne, weight gain. | Absence of pregnancy despite regular unprotected sex. |
| Diagnosis Criteria | Based on Rotterdam criteria (2 out of 3: cysts, irregular cycles, hyperandrogenism). | Based on failure to conceive over time. |
| Reversibility | Often manageable with lifestyle changes and medication. | Depends on underlying cause; may or may not be reversible. |
Frequently Asked Questions (FAQs) On Fertility Treatment
When should a couple seek medical evaluation for infertility?
Couples should consult a healthcare expert if they have not achieved pregnancy after 12 months of regular, unprotected intercourse. Women over 35 are advised to seek evaluation after 6 months, and those over 40 may consider immediate assessment. This timeline reflects the natural decline in fertility with age and helps avoid delays in identifying treatable causes. Evaluation includes a complete medical history, physical exams, and targeted diagnostic tests.
What are the common causes of infertility in women?
Female infertility can be caused by ovulatory disorders, blocked fallopian tubes, endometriosis, uterine anomalies, and age-related decline in egg quality. These conditions may act alone or in combination, reducing the likelihood of natural conception. A detailed reproductive evaluation helps identify these issues early. Hormonal and imaging tests are usually part of the diagnostic process.
How does in vitro fertilization (IVF) work?
IVF involves stimulating the ovaries to produce multiple eggs, retrieving them, and fertilizing them with sperm in a lab. The resulting embryos are transferred into the uterus. IVF is used for various infertility conditions, including tubal blockages and severe male factor infertility. Success rates vary by age and embryo quality.
Can both partners be infertile at the same time?
Yes, in approximately 20–30% of infertility cases, both partners have contributing factors. These may be unrelated or compounding, making diagnosis and treatment more complex. Joint evaluation is essential for accurate diagnosis and treatment planning. A comprehensive fertility workup includes both partners early in the process.
Is infertility always permanent?
No, infertility is often treatable depending on the underlying cause. Many couples achieve pregnancy through medication, surgery, or assisted reproductive technologies. Advances in treatment options have made parenthood possible for many previously considered infertile. Early evaluation improves chances of successful outcomes.
How is male infertility diagnosed?
Diagnosis typically involves a semen analysis to evaluate sperm count, motility, and morphology. Additional assessments may include hormonal evaluations, genetic testing, and imaging of the reproductive tract. These helps identify causes like varicocele, hormonal disorders, or obstruction. Diagnosis is essential to determine appropriate and effective treatment strategies.
What role does age play in fertility?
Fertility decreases with age, particularly after 35 in women, due to declining egg quantity and quality. Men also experience a gradual decline in sperm quality with age. Advanced maternal age increases the risk of miscarriage and chromosomal abnormalities. Age is a major factor considered when tailoring fertility treatment plans.
Are there tests to assess a woman's ovarian reserve?
Yes, tests like anti-Müllerian hormone (AMH) levels and antral follicle count via ultrasound help evaluate ovarian reserve. These tests estimate the number of remaining eggs and potential response to fertility treatments. They are particularly useful for older women or those with a family history of early menopause. Results help guide decisions on timing and treatment options.
Are fertility treatments successful?
Success rates vary widely depending on age, the cause of infertility, and treatment type. IVF, for example, has higher success rates in younger women and declines with age. ART techniques have improved significantly over the years. Proper evaluation and personalized treatment planning improve outcomes.
How accurate are infertility diagnostic tests?
Infertility diagnostic tests are generally accurate, but may require a combination of results to provide a clear picture. For women, tests like AMH, FSH, and ultrasound imaging assess ovarian reserve and structural health. For men, semen analysis remains the gold standard, with hormonal and genetic testing providing deeper evaluation.
How do doctors determine the best treatment plan for infertility?
Fertility specialists develop treatment plans based on detailed diagnostic results, patient age, medical history, and personal preferences. They may start with less invasive treatments like ovulation induction or IUI and escalate to IVF or ART if needed. Shared decision-making between patients and healthcare experts is key. Plans are customized for maximum effectiveness and safety.
