Paracetamol Dolo 650 - Uses, Side Effects, Composition and Price

PACE Hospitals

Manufactured by: Micro Labs Limited, Hyderabad, Telangana, India.

Composition: Dolo 650 Tablet 15's has PARACETAMOL 650MG, It’s also called as ACETAMINOPHEN

Overview

Dolo-650 medicine comes under non-steroidal anti-inflammatory drugs (NSAIDs) class, it helps in reducing pain, fever, and in higher doses, reduces inflammation.


Dolo 650 tablet has antipyretic substance that reduces fever. Due to antipyretics the hypothalamus override a prostaglandin-induced increase in temperature that help in lowering down the body temperature resulting in reduction in fever.


Due to potential or actual injury, diseases or tissue damage, body form certain chemicals that are responsible for pain and send signals to brain about unpleasant feeling through peripheral nervous system. Dolo 650 tablet has analgesic substance that block formation of these pain responsible chemicals, resulting in the reduction in pain experienced by a person.

Dolo 650 Tablet Uses

Dolo-650 tablet is a very common medicine and often prescribed alone or with one or two medicine to relieve symptoms of fever, nerve pain, and pain during periods, backache, toothache, sore throat, muscle aches, strains and sprains, common colds, migraine, long-term mild to moderate pain, inflammation due to arthritis etc.

Guidelines for Dolo 650 tablet usage

Guidelines for Dolo 650 Tablet Usage

  • Always take medicine with small amount of water before or after food
  • Always a person should take Dolo 650 medicine within prescribed dosage recommended by primary care physician
  • In case of missed or forgotten dosage, don’t overdose to cover up the missed dosage.
  • Person should not stop Dolo 650 as per their choice, follow the prescription advised by primary care doctor 

Dolo 650 Dosage

Your primary care doctor will prescribe Dolo medicine based on your age and weight. Most of the cases physician will recommend 650mg every 4 or 6 hourly for adults. As per initial guidelines 4000 mg was the maximum allowed dosage in a day, now this has been revised to 2600 mg in a day.


As per new guidelines by Drugs Controller General of India (DCGI) - Central Drugs Standard Control Organization of the Government of India, adult patients can take maximum 2600 mg of Dolo 650 tablet in a day, every 4 to 6 hourly under the medical supervision.

Dolo 650 Medicine Interactions with Foods, Drugs and Diseases

If a person is having any of these conditions or problems such as allergic skin problems, kidney disease, heart disease, a low sodium level in the body, liver disease, breathing problems, heavy alcohol consumption, persistent headache alcoholic drinkers should consult before taking Dolo-650 tablet for their medical condition.


  • Food interactions - avoid consuming alcohol and foods containing alcohol, caffeinated food and beverages such as tea, coffee, cola or chocolate.
  • Drug interactions - If a person is on certain medications such as blood thinners (warfarin), aspirin, cholestyramine, ibuprofen, muscle relaxer (tizanidine), and anti-nausea agents (domperidone or metoclopramide) should avoid taking Dolo 650.
  • Disease interactions - Person with alcoholism, liver disease, chronic kidney disease, IBD, pancreatitis, peptic ulcer, ulcerative colitis, coronary artery disease, and cardiac conditions should use the medication under the supervision of doctor.
Common side effects of Dolo 650

Dolo 650 Side Effects

Generally, it is observed that Dolo 650 tablet doesn’t cause any side effects. However, in some cases, these are some common side effects experienced by a person.


  • Stomach pain, indigestion
  • Malaise (sense of not feeling well, with diffuse pain, fatigue or lack of interest in activities)
  • Nausea, vomiting
  • Low blood pressure
  • Dizziness, drowsiness
  • Diarrhoea etc.
Serious side effects of Dolo 650 tablet

Very rarely, Dolo 650 may cause some serious side effects, it may include:


  • Partial or complete collapse of the lung (Atelectasis), reduced lung function
  • Abnormal liver function, liver damage
  • Skin rashes
  • Increased heartbeat
  • Temporary difficult to speak or breathe (Spasm of the Larynx)
  • Swelling of face, lips, tongue and/or throat
  • Trouble breathing and suffocation (Angioedema of Larynx)
  • Shortness of breath, wheezing
  • Abnormal Nervous system
  • Low platelets counts
  • Decreased white blood cells counts


Consult your primary care physician if experience any of these symptoms, prolonged symptoms may become severe in long term.

Storage 

Dolo 650 should be stored in a dry and dark place under room temperature not exceeding 30ºC. Keep medicine away from heat, open air and direct sunlight, It can have harmful effects to the body.


It’s always recommended keeping your medicine with you whenever travelling and take it as prescribed by your doctor.

Expiration Date of Paracetamol Dolo 650

Paracetamol Dolo 650 has expiry of 3 years 10 months from the date of manufacturing. You can see the backside of Dolo 650 Tablet 15's strip for expiration date. It is always advised to check expiry date when buying or taking medicines to avoid adverse effects.

Dolo 650 price

Maximum retail price as per year 2024: Rs. 33.76 for one strip (15 tablets in each strip). Dolo 650mg is available at mostly each and every pharmacy.

Frequently Asked Questions (FAQs) on Dolo-650


  • How many days can I take dolo-650?

    There is no such limitation. Dolo 650 can be taken for two days or three days or four days. It is a medicine to treat the underlying symptoms of the disease, but not to treat the disease. When the patient has fever or pain the Dolo can be taken under medical supervision.

  • Is dolo-650 good for fever?

    Yes, Dolo-650 is good for fever symptom due to its antipyretic substance. Antipyretic override hypothalamus helps to maintain your body's internal balance (homeostasis) by reducing body temperature.

  • Can I take dolo-650 for headache?

    Yes, Dolo 650 or paracetamol has analgesic effect can be taken for headache. It helps in decreasing pains, mainly headaches, migraine, kind of headaches and tension type of headaches. It has a central analgesic action similar to aspirin. Which helps in raising pain threshold, helps in decreasing pain.

  • How many dolo-650 tablet per day can I take?

    As per new guidelines released by DCGI, maximum allowed dosage of Dolo-650 is 2600 mg in a day. Adults can take maximum 4 tablets of Dolo-650 in a day, advised by primary care physician.

  • Is dolo-650 safe during pregnancy?

    Yes, it is completely safe to use Dolo 650 during first trimester, second trimester or third trimester of pregnancy within the prescribed dosages by your gynaecologist or primary care physician.

Is dolo-650 safe?

Dolo 650 is a brand name, and it has 650 MG of paracetamol is also called Acetaminophen. It comes under non-steroidal anti-inflammatory drugs (NSAIDs) drug class. Paracetamol has antipyretic and analgesic, which helps in decreasing fever and pain, and it has a minimal anti-inflammatory action. Dolo 650 is safe to use within prescribed dosage under the supervision of the doctor for related medical conditions.

Is dolo-650 pain killer and can it be taken for pain relief?

Yes, Dolo 650 or paracetamol not only helps in reducing fevers but also has analgesic effect reducing pain, pain relief. It is helpful in conditions like headache, mild migraine, musculoskeletal pains, dysmenorrhoea pains, reducing knee pains etc.

Is paracetamol dolo-650 a steroid?

No, paracetamol dolo-650 is not a steroid. It doesn't come under the steroids (anti-inflammatory) drug classification.

Is paracetamol dolo-650 an antibiotic?

No, paracetamol dolo-650 is not an antibiotic. It doesn't come under the antibiotic drug classification.

Can we take dolo-650 without fever?

Paracetamol Dolo 650 not only helps in reducing the fever, it also has an analgesic effect. It can help in reducing pains, mainly in headaches, musculoskeletal pains, migraine pains as also helps in reducing joint pains like osteoarthritic.

Can I take dolo-650 and cetirizine together?

Dolo 650 comes under non-steroidal anti-inflammatory drug (NSIDs) class whereas cetirizine comes under antihistamines drug class. Both can be taken in combination or can be taken simultaneously without any adverse effect.

Can you take aspirin and paracetamol dolo-650 together?

Aspirin and paracetamol Dolo-650 both comes under NSAIDs. It's better to avoid two non-steroidal anti-inflammatory drugs at a time. As it can lead to increased dosage of NSAID drugs and can cause some kind of gastritis, stomach upset, problems related to kidneys and other adverse drug reactions. So it’s always advised better not to consume two NSAIDs drugs in combination or to be taken at a time.

How much time dolo-650 take to work?

After taking Dolo 650 or paracetamol, it takes half an hour to one hour for absorption. The peak effect of paracetamol dolo 650 starts within one hour after ingestion. And half-life of the paracetamol dolo 650 is around three to three and half hours, maximum duration of action of is around five to six hours.

Can dolo-650 be used for neck pain?

Dolo 650 or paracetamol has a central analgesic action like aspirin. It raises pain threshold, not only used for fevers, it can be used for musculoskeletal pains like neck pains, backache, osteoarthritic, kind of pains as well as headaches like migraine.

Can dolo-650 be used for throat pain or sore throat?

Usually, sore throat or throat pain is occurs because of inflammation of the throat or pharyngeal wall. Dolo 650 has a weak anti-inflammatory component because of which it is not helpful much in sore throat or throat pain, which is because of inflammation.

Can feeding mother take dolo-650?

Feeding mother can use the dolo-650, there is no evidence that it will harm baby.

Is it safe to take a Dolo 650 tablet after getting a covid-19 vaccine?

It is absolutely safe to take a Dolo 650 tablet after getting a COVID-19 vaccine when a person developed mild symptoms like body pain, fever, headache etc.


Note: Without having any symptoms, a person should not take Dolo 650 tablet.

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